{"title":"Primary cells","description":"","products":[{"product_id":"nhek-c-adult-pooled-500-000-cells","title":"NHEK-c adult pooled 500,000 cells","description":"\u003cp\u003ePrimary Normal Human Epidermal Keratinocytes (NHEK) are available from single or from pooled donors isolated from the epidermis of juvenile foreskin or adult skin from different locations like the face, the breasts, the abdomen, and the thighs. They are the major cell type in the epidermis, making up about 90% of the cells.\u003cbr\u003e\u003cbr\u003eEpidermal keratinocytes originate in the stratum basale and move up through the layers of the epidermis. During this movement, they undergo gradual differentiation and morphology changes until they reach the stratum corneum, where they form a layer of nucleus-free, flat, and highly keratinized squamous cells. This layer forms an effective barrier to the entry of infectious agents into the body and minimizes moisture loss.\u003cbr\u003e\u003cbr\u003eKeratinocytes are also able to produce a variety of cytokines, growth factors, interleukins and complement factors. Therefore keratinocytes are important for wound healing, inflammation, and immune response.\u003cbr\u003e\u003cbr\u003e\u003ca href=\"https:\/\/promocell.com\/normal-human-dermal-fibroblasts-nhdf.html\" rel=\"noopener\" target=\"_blank\"\u003eNormal Human Dermal Fibroblasts (NHDF)\u003c\/a\u003e\u003cspan\u003e \u003c\/span\u003eand\u003cspan\u003e \u003c\/span\u003e\u003ca href=\"https:\/\/promocell.com\/normal-human-epidermal-melanocytes-nhem.html\" rel=\"noopener\" target=\"_blank\"\u003eNormal Human Epidermal Melanocytes (NHEM)\u003c\/a\u003e\u003cspan\u003e \u003c\/span\u003efrom the same donor are available\u003cspan\u003e \u003c\/span\u003e\u003ca href=\"https:\/\/page.promocell.com\/donor-type-request\" rel=\"noopener\" target=\"_blank\"\u003eon request\u003c\/a\u003e.\u003c\/p\u003e\n\u003cp\u003eNHEK are now also available from\u003cspan\u003e \u003c\/span\u003e\u003ca href=\"https:\/\/promocell.com\/specific-donor-cells\/hla-typed-human-primary-cells\/\" rel=\"noopener\" target=\"_blank\"\u003eHLA-typed\u003c\/a\u003e\u003cspan\u003e \u003c\/span\u003eand\u003cspan\u003e \u003c\/span\u003e\u003ca href=\"https:\/\/promocell.com\/specific-donor-cells\/disease-cell-models\/\" rel=\"noopener\" target=\"_blank\"\u003eDiabetes Type I and Type II\u003cspan\u003e \u003c\/span\u003e\u003c\/a\u003edonors.\u003c\/p\u003e","brand":"PromoCell GmbH","offers":[{"title":"Default Title","offer_id":53263698755881,"sku":"C-12006","price":614.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0845\/9976\/7337\/files\/C-12006.png?v=1781380262"},{"product_id":"haoec-c-500-000-cells","title":"HAoEC-c 500,000 cells","description":"\u003cp\u003ePrimary Human Aortic Endothelial Cells (HAoEC) are isolated from the human ascending (thoracic) and descending (abdominal) aorta. They are useful for studying vascular diseases such as thrombosis, atherosclerosis, and hypertension as well as for stent-graft compatibility testing.\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eRequest \u003ca rel=\"noopener\" href=\"https:\/\/promocell.com\/gmp-produced-cell-culture-media\/\" target=\"_blank\"\u003eGMP grade cell culture media\u003c\/a\u003e\u003cspan\u003e \u003c\/span\u003efor endothelial cells.\u003c\/li\u003e\n\u003cli\u003eHAoEC are now also available from \u003ca rel=\"noopener\" href=\"https:\/\/page.promocell.com\/promocell-hla-typed-human-primary-cells-landing\" target=\"_blank\"\u003eHLA-typed\u003c\/a\u003e and \u003ca rel=\"noopener\" href=\"https:\/\/promocell.com\/specific-donor-cells\/disease-cell-models\/\" target=\"_blank\"\u003eDiabetes Type I and Type II\u003c\/a\u003e donors.\u003c\/li\u003e\n\u003c\/ul\u003e","brand":"PromoCell GmbH","offers":[{"title":"Default Title","offer_id":53263698886953,"sku":"C-12271","price":1670.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0845\/9976\/7337\/files\/C-12271.png?v=1781421943"},{"product_id":"hrcepc-c-500-000-cells","title":"HRCEpC-c 500,000 cells","description":"\u003cp\u003ePrimary Human Renal Cortical Epithelial Cells (HRCEpC) are isolated from the cortex of the human kidney and stain positive for cytokeratin. The renal cortex is the outer portion of the kidney between the renal capsule and the renal medulla. It contains the renal corpuscles, the proximal and distal convoluted tubules, and the cortical collecting ducts.\u003c\/p\u003e\n\u003cp\u003eImportant physiological processes like osmoregulation and excretion can be studied with HRCEpC \u003cem\u003ein vitro\u003c\/em\u003e.\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eHRCEpC are now also available from \u003ca href=\"https:\/\/page.promocell.com\/promocell-hla-typed-human-primary-cells-landing\" rel=\"noopener\" target=\"_blank\"\u003eHLA-typed donors\u003c\/a\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e","brand":"PromoCell GmbH","offers":[{"title":"Default Title","offer_id":53263699018025,"sku":"C-12660","price":1745.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0845\/9976\/7337\/files\/C-12660.png?v=1781423947"},{"product_id":"nhek-c-adult-single-donor-500-000-cells","title":"NHEK-c adult single donor  500,000 cells","description":"\u003cp\u003ePrimary Normal Human Epidermal Keratinocytes (NHEK) are available from single or from pooled donors isolated from the epidermis of juvenile foreskin or adult skin from different locations like the face, the breasts, the abdomen, and the thighs. They are the major cell type in the epidermis, making up about 90% of the cells.\u003cbr\u003e\u003cbr\u003eEpidermal keratinocytes originate in the stratum basale and move up through the layers of the epidermis. During this movement, they undergo gradual differentiation and morphology changes until they reach the stratum corneum, where they form a layer of nucleus-free, flat, and highly keratinized squamous cells. This layer forms an effective barrier to the entry of infectious agents into the body and minimizes moisture loss.\u003cbr\u003e\u003cbr\u003eKeratinocytes are also able to produce a variety of cytokines, growth factors, interleukins and complement factors. Therefore keratinocytes are important for wound healing, inflammation, and immune response.\u003cbr\u003e\u003cbr\u003e\u003ca href=\"https:\/\/promocell.com\/normal-human-dermal-fibroblasts-nhdf.html\" rel=\"noopener\" target=\"_blank\"\u003eNormal Human Dermal Fibroblasts (NHDF)\u003c\/a\u003e\u003cspan\u003e \u003c\/span\u003eand\u003cspan\u003e \u003c\/span\u003e\u003ca href=\"https:\/\/promocell.com\/normal-human-epidermal-melanocytes-nhem.html\" rel=\"noopener\" target=\"_blank\"\u003eNormal Human Epidermal Melanocytes (NHEM)\u003c\/a\u003e\u003cspan\u003e \u003c\/span\u003efrom the same donor are available\u003cspan\u003e \u003c\/span\u003e\u003ca href=\"https:\/\/page.promocell.com\/donor-type-request\" rel=\"noopener\" target=\"_blank\"\u003eon request\u003c\/a\u003e.\u003c\/p\u003e\n\u003cp\u003eNHEK are now also available from\u003cspan\u003e \u003c\/span\u003e\u003ca href=\"https:\/\/promocell.com\/specific-donor-cells\/hla-typed-human-primary-cells\/\" rel=\"noopener\" target=\"_blank\"\u003eHLA-typed\u003c\/a\u003e\u003cspan\u003e \u003c\/span\u003eand\u003cspan\u003e \u003c\/span\u003e\u003ca href=\"https:\/\/promocell.com\/specific-donor-cells\/disease-cell-models\/\" rel=\"noopener\" target=\"_blank\"\u003eDiabetes Type I and Type II\u003cspan\u003e \u003c\/span\u003e\u003c\/a\u003edonors.\u003c\/p\u003e\n\u003cp\u003e\u003cbr\u003e\u003c\/p\u003e","brand":"PromoCell GmbH","offers":[{"title":"Default Title","offer_id":53263699607849,"sku":"C-12003","price":759.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0845\/9976\/7337\/files\/C-12003.png?v=1781379980"},{"product_id":"nhek-c-adult-growth-medium-3-pooled-500-000-cells","title":"NHEK-c adult Growth Medium 3 pooled 500,000 cells","description":"\u003cp\u003e\u003cspan\u003ePrimary Normal Human Epidermal Keratinocytes (NHEK) GM3 are available from \u003c\/span\u003e\u003cstrong\u003esingle or from pooled donors\u003c\/strong\u003e\u003cspan\u003e isolated from the epidermis of juvenile foreskin or adult skin from different locations like the face, the breasts, the abdomen, and the thighs. They are the major cell type in the epidermis, making up about 90% of the cells.\u003c\/span\u003e\u003cbr\u003e\u003cbr\u003e\u003cspan\u003eEpidermal keratinocytes originate in the stratum basale and move up through the layers of the epidermis. During this movement, they undergo gradual differentiation and morphology changes until they reach the stratum corneum, where they form a layer of nucleus-free, flat, and highly keratinized squamous cells. This layer forms an effective barrier to the entry of infectious agents into the body and minimizes moisture loss.\u003c\/span\u003e\u003cbr\u003e\u003cbr\u003e\u003cspan\u003eKeratinocytes are also able to produce a variety of cytokines, growth factors, interleukins and complement factors. Therefore keratinocytes are important for wound healing, inflammation, and immune response.\u003c\/span\u003e\u003cbr\u003e\u003cbr\u003e\u003cspan\u003ePrimary Normal Human Epidermal Keratinocytes GM3 are isolated using the improved serum-free and BPE-free \u003c\/span\u003e\u003ca href=\"https:\/\/promocell.com\/keratinocyte-growth-medium-3.html\" rel=\"noopener\" target=\"_blank\"\u003eKeratinocyte Growth Medium 3\u003c\/a\u003e\u003cspan\u003e. The optimized formulation supports a growth of fast proliferating and homogenous cell population without the need for extracellular matrix coatings or feeder cells.\u003c\/span\u003e\u003cbr\u003e\u003cbr\u003e\u003ca href=\"https:\/\/promocell.com\/normal-human-dermal-fibroblasts-nhdf.html\" rel=\"noopener\" target=\"_blank\"\u003eNormal Human Dermal Fibroblasts (NHDF)\u003c\/a\u003e\u003cspan\u003e or \u003c\/span\u003e\u003ca href=\"https:\/\/promocell.com\/normal-human-epidermal-melanocytes-m3-nhem-m3.html\" rel=\"noopener\" target=\"_blank\"\u003eNormal Human Epidermal Melanocytes M3 (NHEM M3)\u003c\/a\u003e\u003cspan\u003e from the same donor are available \u003c\/span\u003e\u003ca href=\"https:\/\/page.promocell.com\/donor-type-request-web\" rel=\"noopener\" target=\"_blank\"\u003eon request\u003c\/a\u003e\u003cspan\u003e.\u003c\/span\u003e\u003cbr\u003e\u003cbr\u003e\u003cspan\u003eNHEK are now also available from \u003c\/span\u003e\u003ca href=\"https:\/\/page.promocell.com\/promocell-hla-typed-human-primary-cells-landing\" rel=\"noopener\" target=\"_blank\"\u003eHLA-typed donors\u003c\/a\u003e\u003cspan\u003e.\u003c\/span\u003e\u003c\/p\u003e","brand":"PromoCell GmbH","offers":[{"title":"Default Title","offer_id":53263699935529,"sku":"C-12016","price":614.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0845\/9976\/7337\/files\/C-12016.png?v=1781380665"},{"product_id":"huvec-c-single-donor-500-000-cells","title":"HUVEC-c single donor 500,000 cells","description":"\u003cp\u003e\u003cstrong\u003ePrimary Human Umbilical Vein Endothelial Cells (HUVEC)\u003c\/strong\u003e are isolated from the vein of the umbilical cord and are commonly used for physiological and pharmacological investigations, such as macromolecule transport, blood coagulation, angiogenesis, and fibrinolysis.\u003c\/p\u003e\n\u003cp\u003e HUVEC  isolated in standard Endothelial Cell Growth Medium. The cells are supplied either from single donors or from pooled donors (from up to four different umbilical cords).\u003c\/p\u003e\n\u003cp\u003eHuman Umbilical Artery Endothelial Cells (HUAEC) from the same donor are available on request.\u003c\/p\u003e\n\u003cp\u003eIn addition, HUVEC are available which are pre-screened for VEGF (vascular endothelial growth factor) response. VEGF is an important signaling protein involved in both vasculogenesis and angiogenesis. In vitro, VEGF has been shown to stimulate endothelial cell mitogenesis, cell migration, sprouting, and microvascular permeability.\u003c\/p\u003e\n\u003cp\u003eRequest GMP grade cell culture media for endothelial cells.\u003cbr\u003eHUVEC are now also available from HLA-typed donors.\u003c\/p\u003e","brand":"PromoCell GmbH","offers":[{"title":"Default Title","offer_id":53263700001065,"sku":"C-12200","price":610.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0845\/9976\/7337\/files\/C-12200.png?v=1781380772"},{"product_id":"huvec-c-pooled-500-000-cells","title":"HUVEC-c pooled 500,000 cells","description":"\u003cp\u003ePrimary Human Umbilical Vein Endothelial Cells (HUVEC) are isolated from the vein of the umbilical cord and are commonly used for physiological and pharmacological investigations, such as macromolecule transport, blood coagulation, angiogenesis, and fibrinolysis.\u003c\/p\u003e\n\u003cp\u003eHUVEC isolated in standard Endothelial Cell Growth Medium. The cells are supplied either from single donors or from pooled donors (from up to four different umbilical cords).\u003c\/p\u003e\n\u003cp\u003e\u003ca href=\"https:\/\/promocell.com\/human-umbilical-artery-endothelial-cells-huaec.html\" rel=\"noopener\" target=\"_blank\"\u003eHuman Umbilical Artery Endothelial Cells (HUAEC)\u003c\/a\u003e from the same donor are available on request.\u003c\/p\u003e\n\u003cp\u003eIn addition, HUVEC are available which are pre-screened for VEGF (vascular endothelial growth factor) response. VEGF is an important signaling protein involved in both vasculogenesis and angiogenesis. \u003cem\u003eIn vitro\u003c\/em\u003e, VEGF has been shown to stimulate endothelial cell mitogenesis, cell migration, sprouting, and microvascular permeability.\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eRequest \u003ca href=\"https:\/\/promocell.com\/gmp-produced-cell-culture-media\/\" rel=\"noopener\" target=\"_blank\"\u003eGMP grade cell culture media\u003c\/a\u003e for endothelial cells.\u003c\/li\u003e\n\u003cli\u003eHUVEC are now also available from \u003ca href=\"https:\/\/page.promocell.com\/promocell-hla-typed-human-primary-cells-landing\" rel=\"noopener\" target=\"_blank\"\u003eHLA-typed donors\u003c\/a\u003e.\u003c\/li\u003e\n\u003c\/ul\u003e","brand":"PromoCell GmbH","offers":[{"title":"Default Title","offer_id":53263700066601,"sku":"C-12203","price":399.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0845\/9976\/7337\/files\/C-12203.png?v=1781381025"},{"product_id":"huvec-c-growth-medium-2-pooled-500-000-cells","title":"HUVEC-c Growth Medium 2 pooled 500,000 cells","description":"\u003cp\u003ePrimary Human Umbilical Vein Endothelial Cells (HUVEC) are isolated from the vein of the umbilical cord and are commonly used for physiological and pharmacological investigations, such as macromolecule transport, blood coagulation, angiogenesis, and fibrinolysis.\u003c\/p\u003e\n\u003cp\u003eHUVEC isolated in \u003ca href=\"https:\/\/promocell.com\/endothelial-cell-growth-medium-2.html\" rel=\"noopener\" target=\"_blank\"\u003eEndothelial Cell Growth Medium 2\u003c\/a\u003e which is free of ECGS and contains additional IGF and VEGF. The cells are supplied either from single donors or from pooled donors (from up to four different umbilical cords).\u003c\/p\u003e\n\u003cp\u003e\u003ca href=\"https:\/\/promocell.com\/human-umbilical-artery-endothelial-cells-huaec.html\" rel=\"noopener\" target=\"_blank\"\u003eHuman Umbilical Artery Endothelial Cells (HUAEC)\u003c\/a\u003e from the same donor are available on request.\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003ca href=\"https:\/\/promocell.com\/gmp-produced-cell-culture-media\/\" rel=\"noopener\" target=\"_blank\"\u003eGMP grade cell culture media\u003c\/a\u003e for endothelial cells.\u003c\/li\u003e\n\u003cli\u003eHUVEC 2 are now also available from \u003ca href=\"https:\/\/page.promocell.com\/promocell-hla-typed-human-primary-cells-landing\" rel=\"noopener\" target=\"_blank\"\u003eHLA-typed donors\u003c\/a\u003e.\u003c\/li\u003e\n\u003c\/ul\u003e","brand":"PromoCell GmbH","offers":[{"title":"Default Title","offer_id":53263700230441,"sku":"C-12208","price":413.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0845\/9976\/7337\/files\/C-12208.png?v=1781381221"},{"product_id":"hdmec-c-adult-500-000-cells","title":"HDMEC-c adult 500,000 cells","description":"\u003cp\u003ePrimary Human Dermal Microvascular Endothelial Cells (HDMEC) are isolated from the dermis of juvenile foreskin and adult skin (different locations). Since the dermis contains blood and lymphatic capillaries, HDMEC comprise Blood and Lymphatic Microvascular Endothelial Cells. Both have a common origin and can be identified by several markers.\u003c\/p\u003e\n\u003cp\u003eIn addition, HDMEC are available which are pre-screened for VEGF (vascular endothelial growth factor) response. VEGF is an important signaling protein involved in both vasculogenesis and angiogenesis. \u003cem\u003eIn vitro\u003c\/em\u003e, VEGF has been shown to stimulate endothelial cell mitogenesis, cell migration, sprouting, and microvascular permeability.\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eRequest \u003ca href=\"https:\/\/promocell.com\/gmp-produced-cell-culture-media\/\" rel=\"noopener\" target=\"_blank\"\u003eGMP grade cell culture media\u003c\/a\u003e for endothelial cells.\u003c\/li\u003e\n\u003cli\u003eHDMEC (adult) are now also available from \u003ca href=\"https:\/\/page.promocell.com\/promocell-hla-typed-human-primary-cells-landing\" rel=\"noopener\" target=\"_blank\"\u003eHLA-typed donors\u003c\/a\u003e.\u003c\/li\u003e\n\u003c\/ul\u003e","brand":"PromoCell GmbH","offers":[{"title":"Default Title","offer_id":53263700328745,"sku":"C-12212","price":1422.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0845\/9976\/7337\/files\/C-12212.png?v=1781381561"},{"product_id":"hdlec-c-500-000-cells","title":"HDLEC-c 500,000 cells","description":"\u003cp\u003ePrimary Human Dermal Lymphatic Endothelial Cells (HDLEC) are a subpopulation of the Human Dermal Endothelial Cells. They are isolated from the dermis of juvenile foreskin and adult skin (different locations) from a single donor.\u003c\/p\u003e\n\u003cp\u003e\u003ca href=\"https:\/\/promocell.com\/human-dermal-blood-endothelial-cells-hdbec.html\" rel=\"noopener\" target=\"_blank\"\u003eHuman Dermal Blood Endothelial Cells (HDBEC)\u003c\/a\u003e from the same donor are available on request.\u003c\/p\u003e\n\u003cp\u003eLymphatic vessels transport excess fluids from tissues to the circulatory system and are a major component of the immune system. The transported fluid is nearly cell free. The vessels are highly permeable, because they lack a continuous basal membrane. Lymphatic endothelial cells are involved in pathological alterations of the lymphatic system. During tumor lymphangiogenesis, the lymphatic endothelial cells build new vessels that infiltrate tumors, attract tumor cells, and induce tumor cell metastasis.\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eRequest  \u003ca href=\"https:\/\/promocell.com\/gmp-produced-cell-culture-media\/\" rel=\"noopener\" target=\"_blank\"\u003eGMP grade cell culture media\u003c\/a\u003e for endothelial cells.\u003c\/li\u003e\n\u003cli\u003eHDLEC are now also available from \u003ca href=\"https:\/\/page.promocell.com\/promocell-hla-typed-human-primary-cells-landing\" rel=\"noopener\" target=\"_blank\"\u003eHLA-typed donors\u003c\/a\u003e.\u003c\/li\u003e\n\u003c\/ul\u003e","brand":"PromoCell GmbH","offers":[{"title":"Default Title","offer_id":53263700427049,"sku":"C-12216","price":1322.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0845\/9976\/7337\/files\/C-12216.png?v=1781381622"},{"product_id":"hdlec-c-adult-500-000-cells","title":"HDLEC-c adult  500,000 cells","description":"\u003cp\u003ePrimary Human Dermal Lymphatic Endothelial Cells (HDLEC) are a subpopulation of the Human Dermal Endothelial Cells. They are isolated from the dermis of juvenile foreskin and adult skin (different locations) from a single donor.\u003c\/p\u003e\n\u003cp\u003e\u003ca href=\"https:\/\/promocell.com\/human-dermal-blood-endothelial-cells-hdbec.html\" rel=\"noopener\" target=\"_blank\"\u003eHuman Dermal Blood Endothelial Cells (HDBEC)\u003c\/a\u003e from the same donor are available on request.\u003c\/p\u003e\n\u003cp\u003eLymphatic vessels transport excess fluids from tissues to the circulatory system and are a major component of the immune system. The transported fluid is nearly cell free. The vessels are highly permeable, because they lack a continuous basal membrane. Lymphatic endothelial cells are involved in pathological alterations of the lymphatic system. During tumor lymphangiogenesis, the lymphatic endothelial cells build new vessels that infiltrate tumors, attract tumor cells, and induce tumor cell metastasis.\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eRequest  \u003ca href=\"https:\/\/promocell.com\/gmp-produced-cell-culture-media\/\" rel=\"noopener\" target=\"_blank\"\u003eGMP grade cell culture media\u003c\/a\u003e for endothelial cells.\u003c\/li\u003e\n\u003cli\u003eHDLEC are now also available from \u003ca href=\"https:\/\/page.promocell.com\/promocell-hla-typed-human-primary-cells-landing\" rel=\"noopener\" target=\"_blank\"\u003eHLA-typed donors\u003c\/a\u003e.\u003c\/li\u003e\n\u003c\/ul\u003e","brand":"PromoCell GmbH","offers":[{"title":"Default Title","offer_id":53263700492585,"sku":"C-12217","price":1247.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0845\/9976\/7337\/files\/C-12217.png?v=1781381892"},{"product_id":"hcaec-c-500-000-cells","title":"HCAEC-c 500,000 cells","description":"\u003cp\u003ePrimary Human Coronary Artery Endothelial Cells (HCAEC) are isolated from the coronary arteries (the right and the left coronary artery, including the anterior descending and the circumflex branches) from single donors. They are crucially involved in the regulation of coronary blood flow and cardiac functions and are consequently useful for \u003cem\u003ein vitro\u003c\/em\u003e studies of diseases such as thrombosis, atherosclerosis, and hypertension. HCAEC are also suitable for studying functional vasodilators, such as prostacyclin, bradykinin, or nitric oxide.\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eRequest  \u003ca rel=\"noopener\" href=\"https:\/\/promocell.com\/gmp-produced-cell-culture-media\/\" target=\"_blank\"\u003eGMP grade cell culture media\u003c\/a\u003e for endothelial cells.\u003c\/li\u003e\n\u003cli\u003eHCAEC are now also available from \u003ca rel=\"noopener\" href=\"https:\/\/page.promocell.com\/promocell-hla-typed-human-primary-cells-landing\" target=\"_blank\"\u003eHLA-typed\u003c\/a\u003e and \u003ca rel=\"noopener\" href=\"https:\/\/promocell.com\/specific-donor-cells\/disease-cell-models\/?__hstc=62349491.ceafb7de1b824c3e5bec190e9e08ec73.1721392150282.1721720731150.1721754862342.6\u0026amp;__hssc=62349491.32.1721754862342\u0026amp;__hsfp=3598200494\" target=\"_blank\"\u003eDiabetes Type I and Type II\u003c\/a\u003e donors.\u003c\/li\u003e\n\u003c\/ul\u003e","brand":"PromoCell GmbH","offers":[{"title":"Default Title","offer_id":53263700558121,"sku":"C-12221","price":1711.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0845\/9976\/7337\/files\/C-12221.png?v=1781382044"},{"product_id":"hpmec-c-500-000-cells","title":"HPMEC-c 500,000 cells","description":"\u003cp\u003e\u003cstrong\u003ePrimary Human Pulmonary Microvascular Endothelial Cells (HPMEC)\u003c\/strong\u003e are isolated from the lung from a single donor. Since lung tissue contains blood and lymphatic capillaries, HPMEC comprise Blood and Lymphatic Microvascular Endothelial Cells. The cells are routinely analyzed by immunofluorescent staining: they stain positive for CD31 and von Willebrand factor and negative for smooth muscle α-actin.\u003c\/p\u003e\n\u003cp\u003eThe lung has a vast endothelial surface area, which is essential for the exchange of gases. HPMEC are most appropriate for studying human lung diseases.\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eRequest  \u003ca rel=\"noopener\" href=\"https:\/\/promocell.com\/gmp-produced-cell-culture-media\/\" target=\"_blank\"\u003eGMP grade cell culture media\u003c\/a\u003e for endothelial cells.\u003c\/li\u003e\n\u003cli\u003eHPMEC are now also available from \u003ca rel=\"noopener\" href=\"https:\/\/page.promocell.com\/promocell-hla-typed-human-primary-cells-landing\" target=\"_blank\"\u003eHLA-typed donors\u003c\/a\u003e.\u003c\/li\u003e\n\u003c\/ul\u003e","brand":"PromoCell GmbH","offers":[{"title":"Default Title","offer_id":53263703048489,"sku":"C-12281","price":1713.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0845\/9976\/7337\/files\/C-12281.png?v=1781422144"},{"product_id":"hcmec-c-500-000-cells","title":"HCMEC-c 500,000 cells","description":"\u003cp\u003e\u003cstrong\u003ePrimary Human Cardiac Microvascular Endothelial Cells (HCMEC) \u003c\/strong\u003eare isolated from heart ventricles from a single donor. The cells are routinely analyzed by immunofluorescent staining: they stain positive for CD31 and von Willebrand factor and negative for smooth muscle α-actin.\u003c\/p\u003e\n\u003cp\u003eHCMEC play an important role in the physiological regulation of coronary blood flow and capillary exchange. Medical conditions such as hypertrophy, ischemia, hypertension, and diabetes mellitus are associated with endothelial dysfunction.\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eRequest  \u003ca href=\"https:\/\/promocell.com\/gmp-produced-cell-culture-media\/\" rel=\"noopener\" target=\"_blank\"\u003eGMP grade cell culture media\u003c\/a\u003e for endothelial cells.\u003c\/li\u003e\n\u003cli\u003eHCMEC are now also available from \u003ca href=\"https:\/\/page.promocell.com\/promocell-hla-typed-human-primary-cells-landing\" rel=\"noopener\" target=\"_blank\"\u003eHLA-typed donors\u003c\/a\u003e.\u003c\/li\u003e\n\u003c\/ul\u003e","brand":"PromoCell GmbH","offers":[{"title":"Default Title","offer_id":53263703114025,"sku":"C-12285","price":1289.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0845\/9976\/7337\/files\/C-12285.png?v=1781422334"},{"product_id":"nhdf-c-adult-500-000-cells","title":"NHDF-c adult 500,000 cells","description":"\u003cp\u003e\u003cstrong\u003ePrimary Normal Human Dermal Fibroblasts (NHDF)\u003c\/strong\u003e are isolated form the dermis of juvenile foreskin or adult skin from different locations such as face, breast, abdomen, and thighs.\u003c\/p\u003e\n\u003cp\u003eThey can be used for wound healing studies and dermatological research to investigate diseases like scleroderma, fibrosarcoma, fibrosis, xeroderma pigmentosum, and histiocytoma. Moreover, fibroblasts are important for cancer research, tissue regeneration, and tissue engineering studies.\u003c\/p\u003e\n\u003cp\u003e\u003ca rel=\"noopener\" href=\"https:\/\/promocell.com\/normal-human-epidermal-keratinocytes-nhek.html\" target=\"_blank\"\u003eNormal Human Epidermal Keratinocytes (NHEK)\u003c\/a\u003e\u003cspan\u003e \u003c\/span\u003eand Normal Human Epidermal Melanocytes (NHEM) from the same donor are available \u003ca rel=\"noopener\" href=\"https:\/\/page.promocell.com\/donor-type-request\" target=\"_blank\"\u003eon request\u003c\/a\u003e.\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eRequest  \u003ca rel=\"noopener\" href=\"https:\/\/promocell.com\/gmp-produced-cell-culture-media\/\" target=\"_blank\"\u003eGMP grade cell culture media\u003c\/a\u003e for fibroblasts.\u003c\/li\u003e\n\u003cli\u003eNHDF are now also available from \u003ca rel=\"noopener\" href=\"https:\/\/page.promocell.com\/promocell-hla-typed-human-primary-cells-landing\" target=\"_blank\"\u003eHLA-typed donors\u003c\/a\u003e.\u003c\/li\u003e\n\u003c\/ul\u003e","brand":"PromoCell GmbH","offers":[{"title":"Default Title","offer_id":53263703179561,"sku":"C-12302","price":607.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0845\/9976\/7337\/files\/C-12302.png?v=1781422508"},{"product_id":"hcf-c-500-000-cells","title":"HCF-c 500,000 cells","description":"\u003cp\u003e\u003cstrong\u003ePrimary Human Cardiac Fibroblasts (HCF)\u003c\/strong\u003e are isolated from the ventricles of the adult heart. They play a central role in the maintenance of the extracellular matrix in the normal heart and the synthesis of growth factors and cytokines. Under pathophysiological conditions, cardiac fibroblasts are involved in scar formation after myocardial infarction, cardiac fibrosis, and cardiac hypertrophy. HCF can be used to study such processes \u003cem\u003ein vitro\u003c\/em\u003e.\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eRequest \u003ca href=\"https:\/\/promocell.com\/gmp-produced-cell-culture-media\/\" rel=\"noopener\" target=\"_blank\"\u003eGMP grade cell culture media\u003c\/a\u003e for fibroblasts.\u003c\/li\u003e\n\u003cli\u003eHCF are now also available from \u003ca href=\"https:\/\/page.promocell.com\/promocell-hla-typed-human-primary-cells-landing\" rel=\"noopener\" target=\"_blank\"\u003eHLA-typed donors\u003c\/a\u003e.\u003c\/li\u003e\n\u003c\/ul\u003e","brand":"PromoCell GmbH","offers":[{"title":"Default Title","offer_id":53263705178409,"sku":"C-12375","price":1487.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0845\/9976\/7337\/files\/C-12375.png?v=1781422684"},{"product_id":"hcasmc-c-500-000-cells","title":"HCASMC-c 500,000 cells","description":"\u003cp\u003e\u003cstrong\u003ePrimary Human Coronary Artery Smooth Muscle Cells (HCASMC) \u003c\/strong\u003eare isolated from human coronary arteries and stain positive for smooth muscle α-actin. Coronary arteries supply the heart with blood and obstruction in atherosclerosis causes myocardial infarction.\u003c\/p\u003e\n\u003cp\u003eHCASMC are qualified to study the function of smooth muscle cells in the development of atherosclerotic plaques or in other diseases like hypertension. They are also useful for stent-graft compatibility testing.\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eRequest \u003ca rel=\"noopener\" href=\"https:\/\/promocell.com\/gmp-produced-cell-culture-media\/\" target=\"_blank\"\u003eGMP grade cell culture media\u003c\/a\u003e for smooth muscle cells.\u003c\/li\u003e\n\u003cli\u003eHCASMC are now also available from \u003ca rel=\"noopener\" href=\"https:\/\/page.promocell.com\/promocell-hla-typed-human-primary-cells-landing\" target=\"_blank\"\u003eHLA-typed\u003c\/a\u003e and \u003ca rel=\"noopener\" href=\"https:\/\/promocell.com\/specific-donor-cells\/disease-cell-models\/\" target=\"_blank\"\u003eDiabetes Type I and Type II\u003c\/a\u003e donors.\u003c\/li\u003e\n\u003c\/ul\u003e","brand":"PromoCell GmbH","offers":[{"title":"Default Title","offer_id":53263708422441,"sku":"C-12511","price":1693.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0845\/9976\/7337\/files\/C-12511_647b08f8-5bff-4fa7-950f-2c7556731e88.png?v=1781423071"},{"product_id":"skmc-c-500-000-cells","title":"SkMC-c 500,000 cells","description":"\u003cp\u003e\u003cstrong\u003ePrimary Human Skeletal Muscle Cells (SkMC)\u003c\/strong\u003e are isolated from different skeletal muscles (e.g. Musculus pectoralis major) from adult single donors (lot specific source information is available on request).\u003c\/p\u003e\n\u003cp\u003eNew skeletal muscle cells originate from quiescent satellite cells, which are located in the muscle fibers between the basal lamina and the sarcolemma. Quiescent satellite cells are activated by stimuli such as muscle damage. After activation, the cells, now called myoblasts, start to proliferate and fuse with damaged muscle fibers or with one another forming new myotubes.\u003c\/p\u003e\n\u003cp\u003eSkMC are optimal for \u003cem\u003ein vitro\u003c\/em\u003e muscle studies. They proliferate very well in our mitogen-rich \u003ca href=\"https:\/\/promocell.com\/skeletal-muscle-cell-growth-medium.html\" rel=\"noopener\" target=\"_blank\"\u003eSkeletal Muscle Cell Growth Medium.\u003c\/a\u003e Fusion to myotubes with typical multinucleated syncytia can be induced by using our \u003ca href=\"https:\/\/promocell.com\/skeletal-muscle-differentiation-medium.html\" rel=\"noopener\" target=\"_blank\"\u003eSkeletal Muscle Cell Differentiation Medium\u003c\/a\u003e.\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eRequest  \u003ca href=\"https:\/\/promocell.com\/gmp-produced-cell-culture-media\/\" rel=\"noopener\" target=\"_blank\"\u003eGMP grade cell culture media\u003c\/a\u003e for skeletal muscle cells.\u003c\/li\u003e\n\u003cli\u003eSkMC are now also available from \u003ca href=\"https:\/\/page.promocell.com\/promocell-hla-typed-human-primary-cells-landing\" rel=\"noopener\" target=\"_blank\"\u003eHLA-typed donors\u003c\/a\u003e.\u003c\/li\u003e\n\u003c\/ul\u003e","brand":"PromoCell GmbH","offers":[{"title":"Default Title","offer_id":53263710945577,"sku":"C-12530","price":1544.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0845\/9976\/7337\/files\/C-12530.png?v=1781423454"},{"product_id":"haosmc-c-rr-500-000-cells","title":"HAoSMC-c RR 500,000 cells","description":"\u003cp\u003e\u003cstrong\u003ePrimary Human Aortic Smooth Muscle Cells (HAoSMC) \u003c\/strong\u003eare isolated from plaque-free regions of the human aorta and stain positive for smooth muscle α-actin. The pulsatile pressure produced by the heart causes a cyclic distention of the aorta. The smooth muscle cells in the aortic wall subsequently contract it again. Changes in the arterial wall, associated with vascular diseases such as atherosclerosis and hypertension, strongly influence this process.\u003c\/p\u003e\n\u003cp\u003eHAoSMC are suitable for studying the role of smooth muscle cells under normal or disease conditions \u003cem\u003ein vitro\u003c\/em\u003e.\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eRequest \u003ca href=\"https:\/\/promocell.com\/gmp-produced-cell-culture-media\/\" rel=\"noopener\" target=\"_blank\"\u003eGMP grade cell culture media\u003c\/a\u003e for smooth muscle cells.\u003c\/li\u003e\n\u003cli\u003eHAoSMC are now also available from \u003ca href=\"https:\/\/page.promocell.com\/promocell-hla-typed-human-primary-cells-landing\" rel=\"noopener\" target=\"_blank\"\u003eHLA-typed\u003c\/a\u003e and \u003ca href=\"https:\/\/promocell.com\/specific-donor-cells\/disease-cell-models\/\" rel=\"noopener\" target=\"_blank\"\u003eDiabetes Type I and Type II\u003c\/a\u003e donors.\u003c\/li\u003e\n\u003c\/ul\u003e","brand":"PromoCell GmbH","offers":[{"title":"Default Title","offer_id":53263714353449,"sku":"C-12533","price":1673.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0845\/9976\/7337\/files\/C-12533.png?v=1781423753"},{"product_id":"hob-c-500-000-cells","title":"HOB-c 500,000 cells","description":"\u003cp\u003e\u003cstrong\u003ePrimary Human Osteoblasts (HOB)\u003c\/strong\u003e are isolated from femoral trabecular bone tissue from the knee or hip joint region (lot specific source information is available on request). They stain positive for alkaline phosphatase and can be mineralized using \u003ca rel=\"noopener\" href=\"https:\/\/promocell.com\/osteoblast-mineralization-medium.html\" target=\"_blank\"\u003eOsteoblast Mineralization Medium\u003c\/a\u003e.\u003c\/p\u003e\n\u003cp\u003eOsteoblasts are of mesenchymal origin and are mainly responsible for bone formation and remodeling. \u003cem\u003eIn vivo\u003c\/em\u003e, they produce a collagen type I rich extracellular matrix called the osteoid.\u003c\/p\u003e\n\u003cp\u003eDuring their development, osteoblasts undergo a maturation process called osteogenesis. When they become encased in the bone matrix, they stop proliferating and become osteocytes.\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eHOB are now also available from \u003ca rel=\"noopener\" href=\"https:\/\/page.promocell.com\/promocell-hla-typed-human-primary-cells-landing\" target=\"_blank\"\u003eHLA-typed\u003c\/a\u003e donors.\u003c\/li\u003e\n\u003c\/ul\u003e","brand":"PromoCell GmbH","offers":[{"title":"Default Title","offer_id":53263718285609,"sku":"C-12720","price":1096.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0845\/9976\/7337\/files\/C-12720.png?v=1781424167"},{"product_id":"hcm-c-500-000-cells","title":"HCM-c 500,000 cells","description":"\u003cp\u003e\u003cstrong\u003ePrimary Human Cardiac Myocytes (HCM)\u003c\/strong\u003e are isolated from the ventricles of the adult heart. They are qualified for \u003cem\u003ein vitro\u003c\/em\u003e research on cardiac diseases and for pharmacological studies. Our HCM behave like progenitor cells and are not fully differentiated. They do not spontaneously beat \u003cem\u003ein vitro\u003c\/em\u003e, but unlike freshly isolated rod-shaped myocytes, our HCM can be cultured for at least 15 population doublings. Therefore, when cultured in our Myocyte Growth Medium, HCM are suitable for long-term experiments like investigating the long-term effects of cytokines, toxicological screenings, or cell-cell interactions.\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eRequest  \u003ca rel=\"noopener\" href=\"https:\/\/promocell.com\/gmp-produced-cell-culture-media\/\" target=\"_blank\"\u003eGMP grade cell culture media\u003c\/a\u003e for cardiac myocytes.\u003c\/li\u003e\n\u003cli\u003eHCM are now also available from \u003ca rel=\"noopener\" href=\"https:\/\/page.promocell.com\/promocell-hla-typed-human-primary-cells-landing\" target=\"_blank\"\u003eHLA-typed\u003c\/a\u003e and \u003ca rel=\"noopener\" href=\"https:\/\/promocell.com\/specific-donor-cells\/disease-cell-models\/\" target=\"_blank\"\u003eDiabetes Type I and Type II\/Cardiomypathy\u003c\/a\u003e donors.\u003c\/li\u003e\n\u003c\/ul\u003e","brand":"PromoCell GmbH","offers":[{"title":"Default Title","offer_id":53263721136425,"sku":"C-12810","price":1692.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0845\/9976\/7337\/files\/C-12810_0e3be46b-f043-48bc-be84-5304b809e83f.png?v=1781424483"}],"url":"https:\/\/shop.vingmed.fi\/en\/collections\/primary-cells-1.oembed?page=2","provider":"Vingmed","version":"1.0","type":"link"}